Acetonitrile 99.9% HPLC & ACS Reagent Grade – CAS #75-05-8

Acetonitrile > 99.9% HPLC-Grade & ACS Reagent Grade

Analytical Chemistry Solvents, Multiples Sizes and Chemistry Grades Available

Acetonitrile is one of the most widely used solvents in analytical chemistry due to its exceptional purity, low viscosity, and compatibility with high-sensitivity detection methods. This product is available in HPLC-Grade and ACS Reagent Grade, making it suitable for regulated laboratory workflows and routine analytical applications.

HPLC-grade acetonitrile is manufactured and batch-tested to meet strict purity and UV absorbance limits, ensuring it will not interfere with chromatographic baselines or peak resolution. Its complete miscibility with water makes it ideal for mobile phase preparation and gradient separations.

Common industries served include pharmaceuticals, environmental testing, food & beverage analysis, and forensic laboratories.

What Does “HPLC-Grade” Mean?

HPLC stands for High-Performance Liquid Chromatography, a technique used to separate, identify, and quantify trace components in complex mixtures.

When acetonitrile is labeled HPLC-grade, it meets enhanced purity and UV absorbance specifications to prevent background noise, ghost peaks, or signal interference during analysis.

Acetonitrile 99.9% Key Benefits

• High Purity (greater than or equal to 99.9%) - Carefully refined to remove trace contaminants that can affect analytical accuracy.
• Low UV Absorbance - Provides clean baselines and improved sensitivity in UV-based detection methods.
• Excellent Reproducibility - Supports consistent results across batches, instruments, and validated methods.
• Fully Miscible with Water - Ideal for mobile phase preparation and gradient HPLC workflows.

Acetonitrile 99.9% Applications

Pharmaceutical Analysis

• API impurity profiling
• Drug formulation testing
• Quality control and regulatory compliance

Environmental Testing

• Water and wastewater analysis
• Soil and sediment testing
• Pollutant detection and monitoring

Food & Beverage Testing

• Residue and contaminant analysis
• Nutrient and additive quantification
• Regulatory safety testing

Technical Specifications

Acetonitrile 99.9% Safety & Handling

For industrial and commercial laboratory use only. Not for household or personal use.

• Flammable liquid and vapor
• Use only with adequate ventilation or in a fume hood
• Wear appropriate PPE (gloves, goggles, lab coat)
• Store in a cool, dry, well-ventilated area away from ignition sources

Always consult the Safety Data Sheet (SDS) before handling.